Lincomycin Solution for Injection 30%, 1 mL Ampoule (IM/IV)

Composition:

Each 1 mL ampoule contains:

• Active ingredient: Lincomycin hydrochloride (calculated as 100% lincomycin) – 300 mg

• Excipients: Disodium edetate, benzyl alcohol, water for injection

Indications:

Lincomycin hydrochloride is used for the treatment of purulent-inflammatory diseases caused by gram-positive bacteria sensitive to its action—especially in cases of severe infections caused by organisms resistant to other antibiotics.
It is indicated for use in:

• Acute and chronic osteomyelitis

• Staphylococcal and streptococcal septicemia

• Pneumonia (especially staphylococcal)

• Purulent infections of the skin and soft tissues

• Erysipelas

• Purulent pleurisy

• Septic complications following vascular or cardiac surgery

• Otitis media

• Septic endocarditis

• Arthritis

• As an adjunctive treatment for diphtheria

Dosage and Administration:

Lincomycin is administered via intramuscular (IM) or intravenous (IV) injection.

Adults:

• IM: 600 mg once or twice daily

• IV infusion: 600 mg diluted in 250 mL of isotonic sodium chloride or glucose solution, administered 2–3 times daily over a minimum of one hour

Children:

• IV infusion at a rate of 60–80 drops/minute

• Dose: 10–20 mg/kg every 8–12 hours

• Total daily dose: 15–30 mg/kg divided into two doses (every 12 hours)

• Duration of treatment: Determined by clinical course, usually 7–14 days

• Renal impairment: In patients with reduced kidney function, the dose should be reduced to 25–30% of the standard dose (not exceeding 1.8 g/day)

Contraindications:

• Pregnancy (unless deemed essential for life-saving purposes)

• Use with caution and reduced dosage in patients with severe liver or kidney dysfunction

• Contraindicated in myasthenia gravis

• Not recommended during breastfeeding (passes through placenta and is excreted in breast milk)

• Contraindicated in infants under 1 month of age

Storage:

Store in the original packaging at a temperature not exceeding 30°C.
Do not freeze.
Keep out of reach of children.