Norvasc 5 mg – original amlodipine tablets for controlling blood pressure and angina. 30 tablets.
Amlodipine
Norvasc
Cardiovascular System → Antihypertensive Agents → Calcium Channel Blockers
Each tablet contains:
Active ingredient: Amlodipine besylate, equivalent to 5 mg or 10 mg of amlodipine.
Excipients: Microcrystalline cellulose, anhydrous calcium phosphate, sodium starch glycolate type A, magnesium stearate.
5 mg tablets: White or almost white, emerald-shaped tablets (octagonal with irregular sides). The Pfizer logo is engraved on one side and AML-5 on the other side.
10 mg tablets: White or almost white, emerald-shaped tablets (octagonal with irregular sides). The Pfizer logo is engraved on one side and AML-10 on the other side.
For oral administration, once daily, with a sufficient amount of water (100 mL).
For arterial hypertension and angina, the usual initial dose is 5 mg. Depending on the patient's individual condition, the dose may be increased to 10 mg.
Use in elderly patients: The usual doses are recommended. Dose adjustment is not required.
Use in patients with renal impairment: The usual doses are recommended; however, the slight increase in the half-life (T1/2) should be taken into account.
No adjustment of the Norvasc dosage regimen is required when used concomitantly with thiazide diuretics, beta-adrenergic blockers, or angiotensin-converting enzyme inhibitors.
The duration of treatment is determined by the attending physician.
Use in children (6–17 years): The recommended oral antihypertensive dose in children is 2.5–5 mg once daily. Doses above 5 mg/day have not been studied in this population. The effect of Norvasc on blood pressure in children under 6 years of age is unknown.
The medicine should be used with caution in patients with hepatic impairment, class III–IV non-ischemic chronic heart failure, aortic stenosis, acute myocardial infarction (during the first month after the infarction), and in patients under 18 years of age, as efficacy and safety have not been fully established.
Caution is required when using amlodipine, as well as other calcium channel blockers, in patients with sick sinus syndrome, mitral stenosis, hypertrophic obstructive cardiomyopathy, and arterial hypotension.
