Rhinomaris Advance is a xylometazoline nasal spray that relieves nasal congestion and makes breathing easier. It acts quickly to relieve symptoms of a runny nose.
International Nonproprietary Name: Xylometazoline
Clinical and Pharmacological Group: Otorhinolaryngology — topical vasoconstrictors.
Each spray dose (90 μL) contains:
Active ingredient: Xylometazoline hydrochloride — 45 μg or 90 μg;
Excipients: Sea water, potassium dihydrogen phosphate, purified water.
Nasal decongestant — alpha-adrenergic agonist.
The product is indicated for the following conditions:
Acute respiratory diseases accompanied by rhinitis (runny nose);
Acute allergic rhinitis;
Pollinosis (hay fever);
Sinusitis;
Eustachitis;
Otitis media — as part of combination therapy to reduce swelling of the nasopharyngeal mucosa;
Preparation of patients for diagnostic procedures involving the nasal passages.
The product is contraindicated in the following cases:
Hypersensitivity to xylometazoline or any other component of the product;
Arterial hypertension;
Tachycardia;
Severe atherosclerosis;
Increased intraocular pressure, particularly angle-closure glaucoma;
Atrophic rhinitis;
Hyperthyroidism;
A history of surgery involving the meninges;
Inflammatory diseases of the skin or mucous membrane of the nasal vestibule;
Conditions following transsphenoidal hypophysectomy;
Pregnancy;
Children under 6 years of age for the 90 μg/dose nasal spray;
Children under 2 years of age for the 45 μg/dose nasal spray.
The product must not be used concomitantly with monoamine oxidase (MAO) inhibitors or within 14 days after their discontinuation, with tricyclic or tetracyclic antidepressants, or with other topical vasoconstrictors (decongestants).
Route of administration: Intranasal.
Metered-dose nasal spray — 45 μg/dose
Children aged 2–6 years: 1 spray into each nostril, 1–3 times daily.
Adults and children over 6 years of age: 1–2 sprays into each nostril, 2–3 times daily.
Metered-dose nasal spray — 90 μg/dose
Adults and children over 6 years of age: 1 spray into each nostril, 2–3 times daily.
Do not use the product more than 3 times a day. Children should use the product under adult supervision. The final application is recommended immediately before bedtime.
Clear the nasal passages before use.
Remove the protective cap.
Before first use, press the spray mechanism several times until a uniform mist appears.
Insert the spray nozzle into a nostril and press the ring once. Keep the bottle upright.
Do not spray while holding the bottle horizontally or pointing it downward.
Gentle inhalation through the nose is recommended immediately before spraying.
Replace the protective cap after use.
Each bottle is intended for individual use only.
After completing a course of treatment, the product may be prescribed again only after an interval of several days.
Use for longer than 5–7 days is not recommended. Consult a doctor regarding the duration of use in children.
If the condition does not improve after treatment, symptoms worsen, or new symptoms develop, consult a doctor.
Use the product only for the indications and according to the method of administration and dosage specified in the instructions.
