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Brovensin combines bromhexine and terbutaline to thin mucus and widen the airways. Use as recommended by a doctor.
Dosage Form: Syrup for oral administration.
Description: Pink, viscous liquid.
Each 10 mL of syrup contains:
Active ingredients:
Bromhexine hydrochloride — 8 mg;
Terbutaline sulfate — 2.5 mg;
Guaifenesin — 100 mg.
Excipients: Benzoic acid, citric acid monohydrate, glycerin, Ponceau 4R Supra, propylene glycol, potassium sorbate, polyethylene glycol (1500), sodium saccharin, raspberry flavouring, menthol, 70% sorbitol solution, purified water.
ATC code: R05C.
Combined expectorants (excluding combinations with antitussive medicines).
Brovensin is a combination medicine used for coughs and colds. Its therapeutic effect is due to the pharmacological properties of its components.
Bromhexine hydrochloride is a mucolytic agent with expectorant action. It thins bronchial secretions by depolymerising the acidic mucopolysaccharides they contain and stimulating the secretory cells of the bronchial mucosa, which produce secretions containing neutral polysaccharides. Bromhexine stimulates the production of endogenous surfactant, which maintains the stability of alveolar cells during breathing.
Terbutaline sulfate is an adrenergic agonist that selectively stimulates β2-adrenergic receptors in the bronchi. This produces bronchodilation, increases mucociliary clearance, and reduces swelling of the bronchial mucosa.
Guaifenesin is an expectorant whose action is based on reducing surface tension and the adhesion of mucus to the bronchial mucosa. It enhances the activity of the ciliated epithelium in the bronchi and facilitates mucus clearance from the respiratory tract. Guaifenesin also has anxiolytic effects.
Acute and chronic bronchopulmonary diseases accompanied by difficulty clearing sputum, including:
Bronchial asthma;
Chronic bronchitis;
Pulmonary emphysema;
Chronic obstructive pulmonary disease;
Tracheobronchitis;
Pneumonia;
Pneumoconiosis;
Pulmonary tuberculosis.
Hypersensitivity to any of the medicine's components;
Cardiac arrhythmias;
Impaired liver function;
Gastric or duodenal ulcer disease;
A predisposition to bleeding;
The first trimester of pregnancy and the breastfeeding period;
Children under 8 years of age.
Brovensin is taken orally 30 minutes after a meal. The medicine may be diluted with water or fruit juice.
Children aged 8–12 years: 2.5 mL 3 times daily.
Adults and children over 12 years of age: 5–10 mL 3 times daily.
The duration of treatment is determined by a doctor.
When Brovensin is used concomitantly with sympathomimetics or theophylline, the effect of the terbutaline it contains is enhanced, increasing the likelihood of side effects.
When used concomitantly, guaifenesin enhances the effects of central nervous system depressants and ethanol.
Bromhexine facilitates the penetration of antibiotics (amoxicillin, erythromycin, cephalexin, and oxytetracycline) and sulfonamide medicines into bronchial secretions.
Concomitant use with cardiac glycosides, corticosteroids, bronchodilators, and diuretics is not contraindicated.
The medicine should be used with caution during pregnancy. Brovensin is contraindicated during the first trimester of pregnancy and while breastfeeding.
The 100 mL oral syrup is supplied in an amber-coloured glass bottle with a polypropylene cap.
One bottle, together with a measuring cup and package leaflet, is supplied in a cardboard box.
Store in a dry place, out of the reach of children, at a temperature not exceeding 25°C.
