Avetexi Tablet 20 mg

Composition:

One film-coated tablet contains:

• Tenoxicam — 20 mg

Excipients: lactose monohydrate, corn starch, purified talc, magnesium stearate, hypromellose, titanium dioxide (E171), iron oxide yellow (E172).

Indications:

• Relief of inflammation and pain in osteoarthritis and rheumatoid arthritis

• Short-term treatment of acute inflammatory diseases of the musculoskeletal system, injuries, strains, and other soft tissue injuries

Dosage and Administration:

• Avetexi tablets are taken orally.

• Preferably taken during or after meals.

• The recommended dose is 20 mg once daily at the same time each day.

• Higher doses are not recommended as no significant clinical benefit is observed, and the risk of side effects increases.

• Usually, the treatment duration does not exceed 7 days, but in severe cases, it may be extended up to 14 days.

Side Effects:

• Dizziness, headache

• Pain and discomfort in the epigastric and abdominal area

• Dyspepsia, nausea, vomiting, flatulence, constipation, digestive disorders

• Stomatitis, anorexia

• Gastrointestinal bleeding, gastrointestinal tract perforation, ulcers of the gastrointestinal tract, peptic ulcer sometimes with fatal outcomes (especially in elderly patients)

• Bloody vomiting, bloody stools, oral ulcers, gastritis, dry mouth

• Exacerbation of colitis and Crohn's disease

If any side effect not mentioned in the instructions occurs, the patient should consult the treating physician.

Contraindications:

• Hypersensitivity to the components of the drug, acetylsalicylic acid, and other nonsteroidal anti-inflammatory drugs (NSAIDs)

• Hypersensitivity to salicylates, ibuprofen, and aspirin accompanied by asthma, rhinitis, angioneurotic edema, or urticaria

• Active or history of recurrent peptic ulcer/bleeding, melena, bloody vomiting, perforation caused by NSAIDs, severe gastritis

• Significant liver and kidney dysfunction

• Diabetes mellitus

• Arterial hypertension, heart failure

• Pregnancy and lactation

• Hereditary fructose intolerance, lactase deficiency, glucose-galactose malabsorption

Pregnancy and Lactation:

Use of the drug during pregnancy and breastfeeding is contraindicated.

Storage Conditions:

Tablets should be stored at a temperature not exceeding 25 ºC, in a dry place, protected from light, and out of reach of children.