Avelox Tablets 400 mg

Indications:

Infectious-inflammatory diseases caused by microorganisms sensitive to the drug:

• Exacerbation of chronic bronchitis

• Community-acquired pneumonia

• Acute sinusitis

• Skin and soft tissue infections

Contraindications:

• Pregnancy

• Lactation (breastfeeding)

• Children and adolescents under 18 years of age

• Hypersensitivity to moxifloxacin or any other components of the product

Dosage and administration:

Adults: 400 mg (1 tablet) once daily.

Duration of treatment:

• 5 days for exacerbation of chronic bronchitis

• 10 days for community-acquired pneumonia

• 7 days for acute sinusitis and skin and soft tissue infections
  Treatment with the medication may be continued for up to 14 days if needed.

Patients with renal insufficiency (creatinine clearance >30 ml/min) do not require dosage adjustment.
Tablets should be swallowed whole with a small amount of water, regardless of meals.

Side effects:

Moxifloxacin is generally well tolerated; most side effects (90%) are mild or moderate in severity.

Gastrointestinal system:
Nausea, vomiting, altered taste sensation, diarrhea, abdominal pain, dyspepsia, altered liver function tests, dry mouth, flatulence, loss of appetite, stomatitis, glossitis.

Cardiovascular system:
QT interval prolongation in patients with hypokalemia, tachycardia, peripheral edema, increase or decrease in blood pressure, chest pain, changes in peripheral blood count.

Central and peripheral nervous system:
Insomnia, dizziness, irritability, drowsiness, tremor, paresthesia, confusion, depression, emotional instability.

Respiratory system:
Bronchospasm, dyspnea.

Musculoskeletal system:
Back pain, arthralgia, myalgia.

Genitourinary system:
Vaginal candidiasis, vaginitis.

Allergic reactions:
Rash, itching, urticaria.