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Herbal laxative.
Composition: Castor oil – 50 ml.
Pharmacological group: Herbal laxative.
Pharmacological action: In the alkaline environment of the duodenum, under the action of lipase, castor oil is converted into ricinoleic acid, which, at a concentration of 0.5 ml/l, stimulates intestinal receptors and reflexively enhances peristalsis. Castor oil also disrupts the absorption of electrolytes and water in the intestinal walls, increases water secretion, and enlarges the intestinal content. This stimulates intestinal motility and accelerates bowel emptying. The laxative effect appears 2–6 hours after administration. With a 4 g dose of oil, the absorption of ricinoleic acid is 100%; with a 50 g dose – only 36%; and with a 60 g dose – 10%. To achieve a laxative effect, a 10 g dose of oil is required.
The use of the preparation also causes reflex contraction of the uterine muscle.
Castor oil consists of monounsaturated fatty acids. It is unique among fats and oils because it is the only source of an 18-carbon fatty acid with a hydroxyl group and a double bond. It contains approximately 87% ricinoleic acid, as well as palmitic, oleic, and linoleic acids, which are well absorbed through the skin and support hair root nutrition, strengthening, and growth.
Indications: Used as an adjuvant in complex therapy.
• Acute constipation
• Poisoning
• Food intoxication
Dosage and administration:
As a laxative, adults take 15–30 ml (1–2 tablespoons) once daily. Children aged 12–14 years: 5–15 ml (1–3 teaspoons) once daily.
Treatment duration should be 4–7 days.
Precautions:
It is recommended not to use castor oil as a laxative for more than 3 consecutive days.
Prolonged use may cause digestive disturbances and reduce absorption of vitamins A and D, leading to hypovitaminosis.
Side effects:
• Nausea, abdominal pain
• Digestive disturbances; with frequent use – enterocolitis, A and D vitamin deficiency
Contraindications:
• Chronic constipation
• Acute inflammation of the intestines (including appendicitis)
• Abdominal pain of unknown etiology
• Pregnancy and lactation
• Children under 12 years
Interactions with other drugs:
Taking castor oil with fat-soluble vitamins reduces absorption of vitamins A, D, and K.
M-cholinoblockers (antipyrine, platyphylline) and antispasmodics (papaverine, drotaverine) reduce the effect of castor oil.
Anticholinesterase drugs (neostigmine, rivastigmine) and glycerin enhance the effect of castor oil.
Overdose:
Taking 7 g/kg of castor oil may cause nausea, abdominal pain, vomiting, diarrhea, and dizziness.
Antidotes: atropine sulfate and loperamide.
In case of overdose, oil intake must be stopped, and large amounts of fluids should be consumed.
Use in pediatrics:
Not recommended for children under 12 years due to high sensitivity of the digestive system and risk of dehydration.
Pregnancy and lactation:
Not recommended for use during pregnancy or lactation.
Effect on ability to drive and operate machinery:
No impact.
Dispensing rules:
Pharmaceutical product group III – available without a prescription.
Shelf life: 3 years
Storage conditions:
Store at temperatures not exceeding 25°C, protected from light.
Do not use the product after the expiration date or if visual defects are observed.
Manufacturer: LLC “Neopharm”
Georgia, Tbilisi, David Aghmashenebeli Avenue, 12th km
Tel/Fax: +995 (032) 259-64-46, 259-57-90
