Allopurinol Tablets 100 mg

Composition:

Allopurinol tablets contain 100 mg or 300 mg of the active ingredient allopurinol.
Excipients include: lactose, sodium starch glycolate, povidone, and magnesium stearate.

Indications:

Allopurinol is used for the treatment or prevention of:

• Gout

• During cancer treatment and diuretic therapy

• Kidney stones

• Certain skin conditions

• Specific enzyme disorders, such as Lesch-Nyhan syndrome

Dosage and Administration:

• Tablets should be swallowed with water after meals.

• The appropriate dose is determined by the prescribing physician.

Adults:

• The initial dose is typically 100 mg per day.

• The doctor may gradually increase the dose by 100 mg at weekly intervals until a maintenance dose is achieved, usually 200–600 mg daily.

• In severe cases, the dose may be increased to 700–900 mg per day.

If the patient is receiving cancer therapy, allopurinol should be started 2–3 days prior to treatment, at an initial dose of 200 mg three times daily.

At the beginning of treatment, your doctor may recommend taking colchicine or a non-steroidal anti-inflammatory drug (NSAID) to prevent acute gout attacks.

If the patient has liver or kidney disease, or is taking medications like mercaptopurine or azathioprine, a lower dose will be prescribed.

In patients undergoing kidney dialysis, the recommended dose is 300–400 mg after each dialysis session.

Elderly patients:

A minimum effective maintenance dose is selected by the doctor.

Children under 15 years (for cancer or enzyme disorders):

• Usual daily dose: 10–20 mg per kg of body weight,

• Maximum: 400 mg per day

Possible Side Effects:

Skin reactions:

• Rash, hives, itching, peeling skin, burning sensation, blisters, scratching, redness, sensitivity, or purple spots on the skin

• These may lead to more severe allergic reactions

Stop taking allopurinol and contact your doctor immediately if you experience any of the following:

• Fever and chills

• Headache, muscle pain, feeling unwell

• Mouth, throat, nose, or genital ulcers

• Red and swollen eyes

• Widespread blisters or skin peeling

• Severe hypersensitivity reactions including fever, skin rash, joint pain, abnormal liver and blood test results

• Sudden wheezing, difficulty breathing, swelling of the lips, throat, tongue, or face, sometimes leading to collapse

• Swollen lymph nodes (armpits, groin, or neck)

• Nausea or vomiting

• Changes in liver function

• Diarrhea, muscle pain, back pain, sore throat, chills

• Liver conditions includingjaundice(yellowing of the skin or eyes), abdominal pain, loss of appetite

• Urinary issues

• Tingling, numbness, or muscle weakness

• Chest pain, high blood pressure, slow heart rate

• Blood in the urine or vomit, fever, depression

• Headache, dizziness, drowsiness

• Diabetes, changes in vision orcataracts

• Changes in taste, digestive issues, oily stools

• Balance problems, numbness

• Inability to move muscles or loss of consciousness

• Bruising, bleeding under the skin, fatigue, pale skin, frequent infections

• Painful infected hair follicles (boils)

• High cholesterol levels

• Fluid retention causing swelling

• Hair loss or discoloration

• Mouth ulcers

• Male fertility issues, erectile dysfunction

• Breast enlargement (gynecomastia) in men